Born in 1976 in Rio de Janeiro where she continues to live and work. Maria Nepomuceno studied painting and drawing at prestigious Parque Lage visual arts school before studying Industrial Design at the University of Rio de Janeiro and art and philosophy at the School of Visual Arts in Rio de Janeiro.  

Since the early 2000's Maria Nepomuceno has applied and developed a method of sewing coils of coloured rope in spiral configurations. Over time her constructions have become increasingly complex, creating installations that fill rooms or extend beyond the exhibition space and into their surrounding landscapes. Certain forms recur in Nepomuceno's work, including vessels, hammocks, beads, bulbs, and tubes, but the spiral always remains the central and unifying motif.

Among her solo exhibitions feature “O Grande Espiral”, at Marcantônio Villaça Space, Brasilia, Brazil (2015); “Trans”, at Victoria Miro Gallery, London, UK (2014); “Breathing Time” at Turner Contemporary, London, UK and at the Museum of Modern Art, Rio de Janeiro, Brazil (2013); “Saudades da pintura e de outras coisas" at A Gentil Carioca Lá, Porto, Portugal (2013); "Always in a Spiral" at Magasin 3 in Stockholm, Sweden (2010);“Esfera Dalva”, Galeria A Gentil Carioca, Rio de Janeiro, Brazil (2009); ; “Respiro”, at Galeria A Gentil Carioca, Rio de Jainero, Brasil (2006).

Nepomuceno has participated in group shows at Mana Wynwood, Miami, US (2015); The International Biennial of Contemporary Art of Cartagena de Indias (2014);  Shangai Sculpture Art Space, Shangai, China (2014); Schirn Kunsthalle, Frankfurt (2013), Hangzhou Triennial of Fiber Art, Hangzhou, China (2013), Grand Palais, Paris (2013), IFA Institut, Berlin (2010), Toyota Museum of Contemporary Art, Nagoya (2008), Paraná Museum of Contemporary Art, Brasil (2007); and Paço Imperial, Rio de Janeiro (2007).

Nepomuceno's works are part of important Brazilian and international collections such as Guggenheim de Nova Iorque, Museum of Fine Arts in Boston, Rubell Family Collection, Rio Art Museum, Rio Museum of Modern Art, Gilberto Chateaubriand Collection and the Tiroche DeLeon Collection.